I don't follow what you mean about "Dear Doctor," there is no Prime Directive during the time of Enterprise.
Archer: "Someday my people are going to come up with some sort of a doctrine: something that tells us what we can and can't do out here – should and shouldn't do. But until somebody tells me that they've drafted that directive
, I'm going to have to remind myself every day that we didn't come out here to play God."
Just as bad.