My own predictions for 2100 are very simple, the machines take over, whether the machines be us or they replace us the machines take over, simply because they become more capable than an unmodified human being, and there is no law in the universe that limits machines to less than human intelligence, and since their are no limits, the limits of the human race will be surpassed by machines.
That is an almost childlike simplification of the entire process. And you are maybe unaware that in the many ways that "intelligence" actually manifest, machines have been more intelligent than humans for almost twenty years now. You are, in fact, conflating "intelligence" with the capacity for creative output, which are not at all the same thing.
When you peel the onion of human decision in the development of technology, the next layer down from creative output is goal-setting and prioritizing, another thing that machines do exceptionally poorly by their very nature. This means that even if we develop AIs that are creative enough to design space ships without human input, they still have to be TOLD to design space ships by humans who set the priorities for what kind of space ship is going to be designed. Humans spend less and less of their energy DOING things and resort to simply DECIDING things and making the machines do all the work.
Consequently, that is an eventual death sentence for industrial society, and ultimately for the machines themselves. Because a machine, by its very definition, is a tool
, something wielded by others to do a job. If there is no one to wield it, the machine has no reason to exist and shuts down until someone tells it what to do.