I dimly remember an interview with John Malkovich in which he admitted that, personally, he had no particular interest in spending weeks of his life playing a comic-book super-villain, so he would have to be extremely
well-compensated to even consider it.
Fair enough. There's no reason it has to be every actor's dream to play Dr. Doom or Lex Luthor . . . or the Flash or Spider-Man for that matter.