Tigh would most likely be drinking synthehol. That might make some difference.
Kara would be in a facility similar to the one Tom Paris was in at the beginning of "Caretaker."
I can't see Cottle smoking, as there's no real equivalent in Trek in the 24th Century.
I could see Baltar being a relative of Dr. Soong, especially given his ancestors. Baltar Soong...
What about Cylon Model Six being a white pasty-faced Android with a positronic brain?