A is for Apollo, interpreted as a god by some of man's ancestors.
B is for Balok, a representative of the First Federation.
C is for Cortez
, USS, a Federation starship involved in the Dominion War
D is for the Dominion, the most lethal enemy yet encountered by the Federation and her allies.
E is for Everybody knows that the most lethal enemy encountered by the Federation is the Borg. Picard said so and he'd never lie to me.