More Khan and Nero, than Khan and Picard.
Both have a dead wife they have to revenge.
Both blame a Starfleet officer for their own personal problems.
Both use those earwig things to control folks.
Both wore grunge-club clothing.
Both laid their hands on a super weapon that was developed in the Federation.
Both were "imprisoned" for a protracted period of time (Ceti Alpha/Klingon prison).
And both failed to saved their wives, Khan was unable, and Nero simply forgot to beam her off of Romulus.