I've never been a huge fan of how this retcon of Bashir's character was handled. From a certain point of view, it can really be seen as character assassination (because it basically reveals he has been a fraud all along). Then there's also the fact that they tried to turn him into DS9's Data/Spock, which worked so poorly that they then basically dropped it.
While it produces a couple of decent moments later on, I think Section 31 really worked better as a way of making the good Doctor more interesting.
It's true that genetic engineering is a good topic to address. But... for the most part I don't think this ever really produced anything that made the retcon worthwhile. Maybe Statistical Probabilities
, I guess.