Presently sales charts looks positive.
Uchuu Senkan Yamato 2199 10,034+22,375=32,410 (2+) (Xebec, AIC)
2012/05/25 11,169 Vol. 1 (DVD) (Two episodes)
2012/07/27 *8,899 Vol. 2 (DVD) (Four episodes)
2012/05/25 23,726 Vol. 1 (BD)
2012/07/27 21,025 Vol. 2 (BD)
It seems to sell a huge amount the first week and then peter off in the following weeks. I imagine some of those BD sales are foreigners in other Region A countries getting the episodes. If the source includes Amazon sales and the like.
It is not the top selling anime of the year, but its total numbers seem respectible against all but the majorly popular current series...some classic family films...and Gundam.