I think you could set up an interesting and reasonably priced show following some lower-level SHIELD operatives as they poke around in the Marvel movie universe policing up Hydra or Chitauri weapons and keeping other dangerous artifacts and technology out of the wrong hands. Maybe set up the backstories of some lesser known heroes and villains.
I've often thought Phil Coulson, Agent of SHIELD
would be a natural for a TV series. But I guess that's off the table now.