Though I wouldn't mind seeing a continuation of the Nolan films with a certain character (the identity of which I will not reveal), I'm also cool with someone doing something different with Batman.
I would like to see the more fantastical villains get some screen time too like Killer Croc, Man Bat, Mr. Freeze (much better done than B&R), Clayface, etc.
But if the Nolan films continued, they could easily do so with a lot of the 'realistic' villains still left over like Riddler, Penguin, Black Mask, Rupert Thorne, Maxie Zeus, Mr. Zsasz, Jim Gordon Jr., and Deadshot. There's also groups like the Black Glove or the Court of Owls.