I haven't voted in part because of several ships
The Enterprise C was utterly destroyed in battle. Since someone pointed out that the original Defiant was destroyed and no one said no to that, What about the C?
The crew of the Enterprise-C were captured because of the changes to the timeline in Yesterdays Enterprise, leading to Sela's birth.
In the novels they take it further, the battered hulk of the E-C taken to Romulus, stripped of all it's technology, taken down to the planets surface and made a momument outside the Romulan capitol, children taken from all the schools in the city to see it.