Nothing Holmes-like about it, frankly, at least not in terms of distinguishing it from your typical buddy-cop detective show.
I thought plenty about it was Holmes-like. An eccentric detective who has a knack for deductions based on details nobody else notices, but who also has addiction issues and limited social skills and an unconventional way of doing things; a more normal partner/assistant who anchors him; a police detective with whom he has a relationship of mutual dislike (although the character isn't named Lestrade).
If that feels like a standard detective show, maybe that's because most detective fiction owes a debt to the Holmes canon. The archetypal work in a genre often seems cliched in retrospect because everything afterward recycles its tropes. But really, the core strength of the Holmes stories was never in the cases or the story structure as much as in the characters and their relationship. We'll have to see how that plays out on this show.