A ton of podcasts, and I'm behind...
WTF with Marc Maron is pretty great.
StarTalk with Neil Degrass Tyson
KCRW's The Business (show business)
KCRW's The Treatment
KCRW's Martini Shot
The Nerdist Writers Panel
Geek's Guide to the Galaxy
Escape pod (sci fi)
Lightspeed Magazine (sci fi)
The Thrilling Adventure Hour--I HIGHLY recommend this one. It's tales in the style of old time radio. With GREAT stars, Nathan Fillion among them.
This American Life.