they could just as easily have the show a re-imagining of Jekyll and Hyde,
ABC's got two
of those under development.
I'm still waiting for someone to make a vampire show that really interests me. The last time that happened, it was Dark Shadows
and I'm pretty sure my tastes have changed radically since then.
The really overdone tropes are: superheroes; sci fi/fantasy cops; and the Touched by an Angel/Medium