I don't know if you've read the book Hannibal by Thomas Harris but he effectively neutralised Hannibal Lecter by making him become more or less normal at the end of the story. It was a huge betrayal IMO. Apart from that the story was shite anyway.
How so? I've read the novel, and I don't remember him "neutralising" Lecter at all.
An illusion--with intelligence! A malignant vision, with a will of pure evil!