I like Atkinson, but I don't think audiences could take him seriously as Q.
He's in Never Say Never Again
, although he didn't play Q, but another ally of Bond. His character was also played for laughs -- mostly slapstick ones, IIRC. However, if Atkinson were more in the Blackadder
mold than the Mr. Bean
one, I could see him taken more seriously.
That said, who can argue with Hugh Laurie? He'd be terrific.