That movie creeped me out, too, when I went to see it in theaters (for free - I had a screenin' pass). And I have a cheap copy on previously viewed DVD (got it on an uber sale at Hasting's).
A couple of weeks ago when I was in Austin, I took it to a scifi movie meetup that watches bad scifi to make fun of it, and Splice
actually had a few votes until one guy yelled out...
...and every other hand but mine went down.
I had to support my movie, though.