Well, first and foremost, I would like to see the DS9 saga move forward. As an avid reader of the original relaunch, I was of course disappointed that storylines such as the Ascendants arc were not brought to fulfillment. But, having jumped forward, I figure we might as well not jump right back again. Some information could, of course, be provided in the form of memories or what have you, but I would like to see the DS9-R gain some momentum and be exciting again. For that to happen, it needs to advance, not retreat.
Secondly, we have seen that most of the original cast of the show, with the exception of Quark, are no longer on the station. I can only guess that this was done for a specific reason, I suppose either to allow the DS9 novels to follow their stories wherever they may lead, or to allow the series to become primarily focused on a mostly new cast of characters, headed by Captain Ro. Personally, I hope it's option one: I do like to see a mix of old and new characters, as was the case in the original relaunch, but I would prefer to see Kira, Sisko, Odo, Bashir and the others remain involved (or most of them in any event).
I do like the idea of seeing them off the station, though, so I'm personally hoping David Mack plans on using Ro (and probably Dax) in his TNG-oriented trilogy, and that DGRIII (or whoever is charged with furthering the DS9 saga) takes Sisko, Kira and the others off on adventures elsewhere, perhaps on Cardassia, as the potential is virtually limitless in that direction. And a story of that kind would inevitably lead to appearances by Garak