Reznor has an Oscar now; that sort of thing can change one's perception of one's self. You think that if Natalie Portman weren't expecting, that she'd still be interested in PP&Z after her Oscar win? Unlikely, I suspect.
Need I point out Ben Kingsley's turns in Thunderbirds and Bloodrayne?
Or Charlize Theron in Aeon Flux?
Or Michael Caine in, for example, Jaws 4?