Quite so. Al Gore in particular is the subject of some of their harshest wit. The "Man Bear Pig" episode absolutely skewers Gore. "I'm cereal!" But the amazing thing is how they can nail someone weeks, months or even years before the rest of the media catches on, ref. Mel Gibson (who they portrayed as a nutcase) and even Avatar (which they turned into a Smurf movie).
They're very quick. They wrote the Avatar/Smurf thing before the movie was released.
They've got very little use for contemporary American right-wing politics, including American militarism and "social values" conservatism which they mock mercilessly. They tend toward libertarianism and particularly like to make fun of celebrity and of any and all religious institutions. Their basic credo is that "it has to be okay to make fun of everything or it's not okay to make fun of anything."