My main criticism against Isometric is that it can feel awkward controlling a character, since graphics follows diagonals but the controller is horizontal/vertical. Replacing keyboard with mouse control, we'd be into Diablo 2 territory, which obviously works well.
I did a little to my procgen program this evening. It may not look much, but it begins creating a game map from the connectivity worked out earlier. These are the main structural walls defining the layout/flow of a dungeon. Obstacles, doors, collectables, generators and monsters can be added into this. I'm intending for the game screen to show about 16x16 tiles, which is a bit wider than the 12 tile corridor width seen in the left picture.