Doomsday I think wouldn't work unless they were using him in a "Death of Superman" film and they already attempted one several times and failed.
I hate Doomsday. Talk about the most boring villain ever. He does nothing but kill. I want my characters to actually be interesting.
The only time he was interesting was on Smallville when the writers made him human and tried to develop the character. He was one of the few things that I liked about the show.