That would kind of suck for Dylan Baker if the villain does turn out to be The Lizard as everyone has been speculating. Fans of the original trilogy wanting to see him only to possibly have someone else play him in the new trilogy. Christophe Waltz would be pretty interesting since Michael Fassbender was their previous choice and he chose to play the young Erik Lensherr.
Yes, the fact that Fassbender was previously in the frame is interesting, as he and Waltz were both in Inglourious Basterds (incidentally, Fassbender, like Waltz is German-born, though raised in Ireland). When they were making the first Spider-man movie, the role of Green Goblin was originally offered to Nicholas Cage, then John Malkovich before Willem Dafoe. Dafoe and Malkovich had starred in Shadow of the Vampire, which was produced by Cage.
Sucks for Walsh all right. Wasn't there a rumour that Raimi wanted him to be the Lizard in his aborted Spider-man 4 but the studio didn't think that Dylan was a big enough name for the part? (Not like those international superstars Alfred Molina and Thomas Hayden Church ...