When I saw these annotations, I put them in because I was sure that I remembered something specific about this story, which I assumed to be a novel-reference. Turned out, it wasn't a novel reference at all, but rather a reference to the classic old Bloom County
Now there's another can of worms. Opus has appeared in the Pearls Before Swine
strip, which has been known to break the lines betweeen strips (literally) and go wandering the comics page. And of course Bloom County
's Opus, Portnoy and Hodgepodge appeared in one of Peter David's early Trek comics in the form of hallucinations seen by Kirk.