Admiral_Young wrote:

^ Why would they use other villains than Magneto since the core story of "X-Men The First Stand" is the falling out of their friendship?
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Maybe their falling out could be the result of differing opinions on how mutant should deal with threats, or Magneto encountering an anti-human mutant who begins to make him disillusioned with Xavier's vision. Mr Sinister might work out well for that role, seeing how in the comics he'd been manipulating people for decades as well as the mutant race.