Nah, he'd never agree. He's been linked with Firefly
for far too long. Anyone who spent that much time on a show that is diametrically opposed to Trek in all regards, is not going to WANT to do Trek in the first place. Besides, the Browncoats would never forgive him for jumping ship to the 'enemy'.
(Ron Glass doesn't count, since he was on Voyager
first, before he ever played Book)