Some of these are really hard to kill. They defend themselves well. What can work is to download Malwarebytes on another computer. Then put it on a flashdrive. Then rename the executable (.exe file) to something else (like killit.exe) Then take the flashdrive to the infected machine and run the executable. Malwarebytes should do the job for you, if you have the latest version. Use the update option until it says there are no more updates.
Sometimes the malware makers get ahead of the anti-malware folks. You may have to wait for the version that addresses your problem.