Considering how Tim Burton handled
Sleepy Hollow, I doubt his version of
Frankenstein would be particularly true to the book. There have already been some fairly authentic adaptations of the book, including one with Kenneth Branagh as Victor and Robert DeNiro as the creature, and a 1992 TV miniseries with Patrick Bergin and Randy Quaid in those respective roles.
Besides, didn't Tim Burton already do his own version of a Frankenstein story, namely
Edward Scissorhands?