I wonder if Viggo Mortensen will be in this one.
Cronenberg has been on a roll lately (much like a fly landing in your Swiss roll ...), with both A History of Violence and Eastern Promises being among his best work. Which bodes well for him revisiting arguably his best known movie.
This is admittedly a slightly odd, even retrograde choice for him but I'm sure he has his reasons. If the 1980s version reflected fears about AIDS, then doubtless he plans to look at modern topics or fears like genetics or viral warfare in this version. And let's face it, even since The Fly, body-shock has remained a feature of his work (e.g. Existenz).