Well, Orions in Starfleet training would imply that, in this timeline, Kirk knows enough about Orion physiology to know sex with them is relatively safe. Can we same about when he bedded the green chick in ToS? He didn't know squat about their body structure. Assuming that coitus is achieved in a similar fashion as human capulation, how the hell did Kirk know she wouldn't lay her eggs in his nut sack? He could have had an Orion/human gestating between his testicles for 15-months for all he knew!
Just some of the random garbage that flits through my mind.