I'd have to go with the Enterprise E or D. Probably the E
If it was the D it would have to be the version from Star Trek Generations. I liked the stations down the sides of the bridge. The original version of D's bridge just didn't seem like it had enough computer stations. The other ships all had computers everywhere lol. I liked the lighting better too.
And of course whichever ship I had would be equipped with a Delta Flyer...
And I'd have to throw some non-canon in there and both the Delta Flyer and my ship would be retro-fitted with the quantum slipstream drive the USS Aventine has.
I'd start at Earth in the Alpha Quadrant... and use my slipstream drive to go back and forth to other quadrants.
That would be my dream ship.