They generally got the important stuff in. The one major piece of adaptation (the change to the ending) I thought was actually quite brilliant.
Acting was pretty good; Haley the obvious standout in the showiest role. Crudup didn't really sound like I thought Manhattan would, but I quickly got used to it. Akerman is probably the weakest link, but she was really hot, so I'm easy to please.
I missed a couple of lines here and there (I really wanted Manhattan to use the term "thermodynamic miracle", for example; for me, that phrase just brought home the think he was making).