Personally, I would have warp drive pretty much phased out by the end of the 25th-Century as slipstream drive becomes more and more commonplace within the Federation and beyond.
All 25th-Century (or later) tech:
LCARS software is eventually gives way to SAGE software.
Isolinear technology is replaced by hyperoptical technology.
Transwarp torpedoes (capable of sustained warp 9.999+ flight with an effective tactical range of 2.74 light-years and a maximum explosive yield of 108 isotons).
Subspace portals as replacements for transporters. Inspired by Iconian gateway technology, it allows instantaneous transport to and from a ship without having to convert matter to energy and back again. Maximum range: 500,000 kilometers.