While I like Powers, I'm not sure it'll make a good transition to the screen. I've read most of it in TPB, and the end of each one usually has me saying "really? *That's* how it ends...?" many of the arcs end with the problem/crisis just ... going away.
Its strength is in the texture, the characters and the commentary on comic books. I'm not sure how satisfying that'll be... but I'll watch.