Emily Deschanel has a bit role as a secretary at the beginning of Spider-Man 2.
John Ratzenberger seemed to pop up all over the place in the late 1970s/early 1980s. He has one line as a Rebel Alliances deck officer on Hoth in Star Wars: The Empire Strikes Back.
He's one of the military guys tracking the nuclear missiles in Superman: The Movie.
And he's one of the NASA mission control guys in Superman II.
Before he was Captain Hollister on Red Dwarf,
Mac Macdonald had a bit role as a colony administrator on LV-426 in Aliens.
Ironically, his role was cut from the theatrical version and didn't resurface until the special edition came out in the early 1990s, after Red Dwarf