I liked the main actress, and I think the dynamic between the characters has potential, but I'm afraid the writing and storyline just didn't grab me that strongly at all. Certainly not like Lost did, or Alias in the beginning.
The main problem for me was this feeling of "been there, done that" throughout. It's certainly well made and well acted, but the fact is, well... X-Files already DID these stories. Years ago. And did them really well too. Watching the previews for upcoming episodes gave me even more of that feeling.
Maybe if Abrams puts the focus more on the larger conspiracy, and throws lots of twists and turns at us, I could overlook all that. But right now it looks like the main emphasis is just going to be on the "weird case of the week." Which just isn't new enough for me.