David's response to a question in a similar thread
only a short time ago:
David Mack wrote:
Yes, you can pretty much just jump in.
The events of the DS9 books aren't really touched upon, nor are those of the New Frontier books, the Corps of Engineers tales, or the Klingon/Gorkon saga. Events from the Titan and TNG books form most of the foundation for the story, though if you read just Greater Than the Sum and Sword of Damocles you'll pretty much be caught up on all of the most immediately relevant backstory.
Anything else you'd need to know is recapped/explained in the books themselves.