Just looking at the figures on the-numbers.com, Aliens Vs Predator: Requiem made less at the US box office than The X Files ($14.9m to $17m), but has so far made another $26 million+ on DVD, bringing its combined gross to $40 million. If X Files performs similarly on DVD, and there's no reason to think it shouldn't, it'll probably end up making Fox a modest profit. That's in the US alone: add 50% to 100% more for the eventual overseas take.
Hardly blockbuster performance, but Fox may yet ask for another movie eventually - if the budget is kept low and, I'd imagine, Carter is asked to make a more overtly commercial movie. Maybe we'll see the werewolf they used for the fake spoilers after all!
Well unfortunately those numbers aren't accurate.
AvP: Requiem made a 41.8 million US and 87 million overseas for a total of nearly 129 million. No budget info is available, so its hard to guess how well it did or didn't do in the theaters.
But it did significantly less then the 1st AvP which grossed 171 million ww on a budget of 60 million.